Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.
نویسندگان
چکیده
Mycobacterium bovis BCG is one of the most commonly administered vaccines. Complications, including disseminated BCG disease, are rare but increasingly reported in immunodeficient children. There is growing recognition of the importance of differences between BCG vaccine strains. We determined the susceptibilities of five genetically distinct BCG vaccine strains to 12 antituberculous drugs.
منابع مشابه
بررسی مولکولی سویه مایکوباکتریوم های جدا شده از ترشحات لنفاوی کودکان مبتلا به لنفادنیت ناشی از واکسیناسیون با واکسن BCG
Background and Aim: In Iran vaccination with Bacillus Calmette-Guérin (BCG) is performed on all newborns within the first days of life for prevention of tuberculosis. It is a live attenuated vaccine and produced from genetically different vaccine strains of Mycobacterium bovis. This vaccine is safe but local adverse reactions such as administration site abscess and lymphadenitis occur in some h...
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Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine available against tuberculosis, and the strains used worldwide represent a family of daughter strains with distinct genotypic characteristics. Here, we report the complete genome sequence of M. bovis BCG Korea, the strain that will be actually used in Korea for vaccine production.
متن کاملThe antituberculous Mycobacterium bovis BCG vaccine is an attenuated mycobacterial producer of phosphorylated nonpeptidic antigens for human gamma delta T cells.
The mycobacterial antigens stimulating human gamma delta T lymphocytes (R. L. Modlin, C. Permitz, F. M. Hofman, V. Torigian, K. Uemura, T. H. Rea, B. R. Bloom, and M. B. Brenner, Nature (London) 339:544-548, 1989; D. H. Raulet, Annu. Rev. Immunol. 7:175-207, 1989) have been characterized recently in Mycobacterium tuberculosis H37Rv as a group of four structurally related nucleotidic or phosphor...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 53 1 شماره
صفحات -
تاریخ انتشار 2009